Latest Research

Artificial Sweeteners Disrupt Microbial Balance & May Worsen Crohn’s Disease Symptoms

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Artificial sweeteners promote dysbiosis (imbalanced gut bacteria) in Crohn’s disease (CD) patients and may worsen the disease and its symptoms. In a series of 3 studies, scientists mixed a low dose of Splenda into the drinking water of mice (who originated from a genetic line of mice with CD). They increased the dose slightly for the second study and ten times for the third study. When compared to control groups of healthy mice that received plain water, there was an increase in ProteobacteriaE. coli, and intestinal wall immune cell reactivity – all signs of dysbiosis. Inflammatory Bowel Diseases

→Takeaway: The lead researcher in the study concluded that Splenda and other artificial sweeteners should be avoided by those with Crohn’s disease, ulcerative colitis, or other digestive diseases, as they can cause inflammation and disease flare-ups. He also suggested in Newsweek that those without these conditions might not need to worry about the potential side effects of Splenda. At Gutbliss, we disagree with this statement and recommend avoiding artificial sweeteners no matter your health status. Recent studies illustrate the detrimental effects of sucralose on the gut microbiome and metabolism.

Leslie Ann received her BA from the University of Notre Dame and has a Master’s degree in Public Health and Nutrition from Johns Hopkins University. With over a decade of experience working in the health and wellness field as a nutritionist, health writer, and project manager, Leslie Ann is the backbone of the Gutbliss team, overseeing operations as well as the strategic mission of Gutbliss Rx, and authoring much of the content on the site. As a certified yoga teacher and personal trainer, she is an avid believer in integrative methods to treat and heal the body.

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