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Gut Bacteria Imbalance Linked To Lupus

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A new study shows a link between gut bacterial imbalances and life threatening forms of lupus for the first time. Blood and stool samples were analyzed in 61 women with systemic lupus erythematosis (SLE) and compared to those of 17 healthy women of matched age and racial backgrounds. Results showed that women with the disease had on average 5 times more Ruminococcus gnavus in the gut. In addition, disease flares (and especially kidney flares) aligned with drastic increases in R gnavus as well as a prevalence of antibodies in the blood that are designed to attach to the bacteria. Annals of Rheumatic Diseases

→Takeaway: Scientists who conducted the study believe that in some instances, bacterial imbalance may be a key player in lupus and its flare-ups. They also hypothesize that bacteria leaking from the gut could trigger the immune response that elicits the disease, and that imbalances in the gut microbiome may play a more critical role than genetics in kidney flare-ups associated with SLE.

Leslie Ann received her BA from the University of Notre Dame and has a Master’s degree in Public Health and Nutrition from Johns Hopkins University. With over a decade of experience working in the health and wellness field as a nutritionist, health writer, and project manager, Leslie Ann is the backbone of the Gutbliss team, overseeing operations as well as the strategic mission of Gutbliss Rx, and authoring much of the content on the site. As a certified yoga teacher and personal trainer, she is an avid believer in integrative methods to treat and heal the body.

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