Microbiome Archives - Page 12 of 13

A Possible Key To Fecal Microbiota Transplantation Success Uncovered

Super-donors could be the key to fecal microbiota transplantation (FMT) success. While FMT is an approved treatment for C. diff infection, it has shown very little promise in treating other dysbiosis (gut bacteria imbalance) –related chronic diseases. A recent review article looked at the evidence supporting the idea of FMT “super donors”; donors who possess specific microbial composition […]

Reduction In Gut Bacteria Species Linked To Depression

A reduction in specific gut bacteria is linked to lower quality of life and incidents of depression. The study – one of the most compelling in illustrating the influence the gut microbiota has on mental health – included 1,063 participants enrolled in Belgium’s Flemish Gut Flora Project. Using DNA sequencing to analyze fecal microbiota, researchers compared […]

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Same Meal Results In Vastly Different Blood Glucose Levels

The same meal results in vastly different blood glucose levels across individuals. For one week a recent study monitored blood glucose levels and measured glucose responses to 46, 898 meals across 800 participants. After finding extreme variations in blood glucose levels in the participants after consuming identical meals, researchers successfully created an algorithm – taking into […]

Gut Bacteria Feed On Colonic Mucus Layer In Absence Of Fiber

In the absence of fiber, gut bacteria eat the protective mucus layer in the colon, the gut’s primary defense mechanism against intestinal pathogens. In a mouse model, the study found that without dietary fiber, both in chronic and intermittent situations, gut bacteria begin consuming secreted mucus glycoproteins as a nutrient source, leading to the destruction […]

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Microbiome Before 2 Years Old Associated With Body Mass Index At Age 12

The gut microbiome in the first 2 years of life strongly correlates with body mass index (BMI) at age 12. A Norwegian study analyzed the gut microbiota at days 4, 10, 30, 120, 365, and 730 and the association with BMI at age 12 in 165 study participants. The researchers also looked at how BMI related […]

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Tongue Microbiome Could Identify Patients With Early Stage Pancreatic Cancer

The tongue microbiome could help identify patients with early stage pancreatic cancer. While previous research shows a strong connection between gut microbial alterations and pancreatic cancer, this study is the first to show changes in the tongue microbiome. 30 patients with early-stage pancreatic cancer and 25 healthy individuals participated in the study. Analysis of the tongue […]

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Sugar Silences A Protein Necessary For Beneficial Gut Bacteria

Sugar silences a protein necessary for the colonization of beneficial gut bacteria. In a mouse model, Yale researchers found that fructose and glucose (sugars extremely abundant in the Western diet) block Roc, a protein essential for the colonization of Bacteroides thetaiotaomicron, a beneficial gut bacteria strain associated with processing fiber rich foods like vegetables. Proceedings of the National […]

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Social Stress Negatively Alters Gut Microbiome

The stress experienced during competitive social situations negatively affects the gut microbiome. The experiment was performed in Syrian hamsters, animals that compete to establish hierarchies of dominant and subordinate groups. The study analyzed gut bacteria before the hamsters met and after they had competed for hierarchical placement, then compared these samples to a control group of […]

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Anesthesia Negatively Alters Gut Microbiome

General anesthesia negatively alters the diversity and composition of the gut microbiome. A 4-hour exposure to anesthesia (Isoflurane) in mice resulted in a significant decrease in microbial diversity and depletion of several commensal bacteria including Clostridiales. Anesthesia & Analgesia →Takeaway: Researchers conclude that anesthesia may lead to dysbiosis (imbalanced gut bacteria) in patients following an operation. If you have […]

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